From the dawn of civilization, humans have sought ways to detect pregnancy before physical signs became evident. Long before the modern hCG pregnancy test revolutionized this process, ancient and medieval cultures devised methods so peculiar and unsettling that they might sound like tales from a horror story to us today. These early tests ranged from sprouting grains to inspecting urine with needles, often blending superstition, rudimentary science, and sheer imagination.

Ancient Egyptian Grain Tests: Sprouting Seeds of Truth
One of the earliest recorded pregnancy tests comes from ancient Egypt, documented in fragments of the Carlsberg Papyrus and more fully in the Berlin Papyrus (also known as the Brugsch Papyrus) from the New Kingdom period. The method was surprisingly straightforward yet strange: a woman would urinate on separate piles of barley and wheat grains. The outcome of this test was interpreted as follows:
If neither grain pile germinated, the woman was not pregnant.
If the barley sprouted, she was pregnant with a male child.
If the wheat sprouted, she was carrying a female child.
Remarkably, a 1963 laboratory experiment lent some credibility to this ancient practice. It found that in 70% of cases, the urine of pregnant women promoted grain germination, while the urine of non-pregnant women and men did not. This suggests that hormonal differences in pregnant women’s urine may have influenced plant growth, giving the Egyptians an unexpectedly scientific edge.
Ancient Greek Oddities: Onions, Honey, and Wombs

The ancient Greeks took a more eccentric approach, relying on methods that seem both comical and cringe-worthy today. One test involved inserting an onion into a woman’s vagina overnight. The logic was rooted in their belief that a non-pregnant woman’s womb was “unobstructed,” allowing the onion’s pungent odor to travel upward and be detectable on her breath the next morning. If she was pregnant, her womb was considered “sealed,” blocking the scent’s path. A variation of this test used perfumed linen applied to the genitals.
Another Greek method, attributed to Hippocrates, required a woman to drink a concoction of honey and water before bed. If she experienced bloating or cramps during the night, it was taken as a sign of pregnancy. While these tests may sound outlandish, they reflect the Greeks’ attempts to link bodily reactions to reproductive states, albeit with questionable accuracy.
Medieval “Piss Prophets” and Urine-Based Divination

By the Middle Ages, pregnancy detection methods grew even more bizarre, with urine becoming the central focus. Enter the “piss prophets,” self-proclaimed experts who claimed they could diagnose pregnancy by observing a woman’s urine through a practice called uroscopy. These medieval diagnosticians relied on the color, clarity, and other properties of urine to make their judgments, often with more flair than precision.
Other medieval tests pushed the boundaries of strangeness. One method involved placing a needle in a woman’s urine; if it rusted red or black, she was deemed pregnant. Another test mixed urine with wine, capitalizing on the alcohol’s reaction with proteins in a pregnant woman’s urine. Surprisingly, this wine-mixing method may have had some scientific merit, as it could produce visible changes in the presence of certain proteins, offering a glimmer of reliability in an era of guesswork.
The Hormonal Breakthrough: From Animal Testing to Modern Kits

It wasn’t until the early 20th century that pregnancy testing began to take on a more scientific form with the discovery of human chorionic gonadotropin (hCG), a hormone present in the urine of pregnant women. Early hCG tests were far from humane or practical. They involved injecting a woman’s urine into an immature female mouse, rat, or rabbit, then killing and dissecting the animal to examine its ovaries. If the urine contained hCG, the animal would go into heat, causing visible changes in its ovaries. However, these tests required high hCG levels to produce results, making them unreliable in early pregnancy.

The modern pregnancy test as we know it began to take shape in the 1960s, with home test kits hitting the U.S. market by the late 1970s. These kits, which detect hCG in urine with high accuracy and ease, marked a dramatic leap forward from the grain-sprouting, onion-sniffing, and animal-sacrificing methods of the past.
A Strange Legacy
The history of pregnancy testing is a testament to human ingenuity, curiosity, and occasional absurdity. From ancient Egyptians watching grains sprout to medieval prophets peering into urine, these early methods may seem like horror stories to modern sensibilities. Yet, they paved the way for the scientific advancements that allow today’s women to confirm pregnancy with a simple, reliable test. The next time you use a pregnancy test, spare a thought for the women of the past who endured onions, needles, and “piss prophets” in their quest for answers.